Dan Marino is the only NFL Quarterback to throw for over 5000 yards in a single season. This NFL record has been in place since 1984. There have been 68 NFL QB's who have thrown for over 4000 yards in the NFL in a single season. Peyton Manning has thrown for over 4000 yards 8 times so far in his career. Dan Marino hit the 4000+ mark 6 times during is hall of fame career. Brett Favre has done it 5 times, and Warren Moon 4 times.

NFL All-Time Leaders	NFL Single Season Leaders
Total Passing Yards Leaders	Passing Yards Leaders
Touchdown Passes Leaders	Touchdown Passes Leaders
Rushing Yards Leaders	Rushing Yards Leaders
Receiving Yards Leaders	Receiving Yards Leaders
Touchdowns Leaders - RB and WR	Rushing Touchdowns Leaders
	Receiving Touchdowns Leaders

Single Season NFL Passing Leaders - 4000+ passing yards
Rk	Player	Team	Yards	Year
1	Dan Marino	Miami Dolphins	5,084	1984
2	Kurt Warner	St. Louis Rams	4,830	2001
3	Tom Brady	New England Patriots	4,806	2007
4	Dan Fouts	San Diego Chargers	4,802	1981
5	Dan Marino	Miami Dolphins	4,746	1986
6	Daunte Culpepper	Minnesota Vikings	4,717	2004
7	Dan Fouts	San Diego Chargers	4,715	1980
8	Warren Moon	Houston Oilers	4,690	1991
T9	Warren Moon	Houston Oilers	4,689	1990
T9	Rich Gannon	Oakland Raiders	4,689	2002
11	Neil Lomax	St. Louis Cardinals	4,614	1984
12	Trent Green	Kansas City Chiefs	4,591	2004
13	Peyton Manning	Indianapolis Colts	4,557	2004
14	Drew Bledsoe	New England Patroits	4,555	1994
15	Lynn Dickey	Green Bay Packers	4,458	1983
16	Dan Marino	Miami Dolphins	4,453	1994
17	Steve Beuerlein	Carolina Panthers	4,436	1999
18	Dan Marino	Miami Dolphins	4,434	1988
19	Drew Brees	New Orleans Saints	4,423	2007
20	Drew Brees	New Orleans Saints	4,418	2006
T21	Peyton Manning	Indianapolis Colts	4,413	2000
T21	Brett Favre	Green Bay Packers	4,413	1995
23	Peyton Manning	Indianapolis Colts	4,397	2006
24	Mark Brunell	Jacksonville Jaguars	4,367	1996
25	Drew Bledsoe	Buffalo Bills	4,359	2002
26	Kurt Warner	St. Louis Rams	4,353	1999
27	Bill Kenney	Kansas City Chiefs	4,348	1983
28	Scott Mitchell	Detroit Lions	4,338	1995
29	Don Majkowski	Green Bay Packers	4,318	1989
30	Jim Everett	Los Angeles Rams	4,310	1989
31	Marc Bulger	St. Louis Rams	4,301	2006
32	Jeff Garcia	San Francisco 49ers	4,278	2000
33	Peyton Manning	Indianapolis Colts	4,267	2003
34	Warren Moon	Minnesota Vikings	4,264	1994
35	Warren Moon	Minnesota Vikings	4,228	1995
36	Brett Favre	Green Bay Packers	4,212	1998
37	Tony Romo	Dallas Cowboys	4,211	2007
38	Jon Kitna	Detroit Lions	4,208	2006
39	Peyton Manning	Indianapolis Colts	4,200	2002
40	Vinny Testaverde	Baltimore Ravens	4,177	1996
41	Steve Young	San Francisco 49ers	4,170	1998
42	Elvis Grbac	Kansas City Chiefs	4,169	2000
43	Brett Favre	Green Bay Packers	4,155	2007
44	Jeff George	Atlanta Falcons	4,143	1995
45	Dan Marino	Miami Dolphins	4,137	1985
46	Peyton Manning	Indianapolis Colts	4,135	1999
47	Brian Sipe	Cleveland Browns	4,132	1980
T48	Peyton Manning	Indianapolis Colts	4,131	2001
T48	Carson Palmer	Cincinnati Bengals	4,131	2007
50	Dan Marino	Miami Dolphins	4,116	1992
51	Tom Brady	New England Patriots	4,110	2005
52	Jay Schroeder	Washington Redskins	4,109	1986
53	Brett Favre	Green Bay Packers	4,091	1999
54	Jake Plummer	Denver Broncos	4,089	2004
55	Brett Favre	Green Bay Packers	4,088	2004
56	Drew Bledsoe	New England Patriots	4,086	1996
57	Dan Fouts	San Diego Chargers	4,082	1979
58	Kerry Collins	New York Giants	4,073	2002
59	Jon Kitna	Detroit Lions	4,068	2007
60	Phil Simms	New York Giants	4,044	1984
61	Peyton Manning	Indianapolis Colts	4,040	2007
62	Trent Green	Kansas City Chiefs	4,039	2003
63	Carson Palmer	Cincinnati Bengals	4,035	2006
64	John Elway	Denver Broncos	4,030	1993
65	Steve Young	San Francisco 49ers	4,023	1993
66	Trent Green	Kansas City Chiefs	4,014	2005
67	Joe Namath	New York Jets	4,007	1967
68	Brad Johnson	Washington Redskins	4,005	1999

** Updated Aug. 26, 2008

Sources:
pro-football-reference.com
databasefootball.com
wikipedia.org
espn.com