Topping off the New England Patriots amazing 2007 season, was Tom Brady surprising Peyton Manning's 49 touchdown passes in a single season. Only 4 QB's have thrown for over 40 TD's in a season, with Dan Marino doing it twice. Brady's mark of 50 TD passes is truly amazing. Brett Favre has never thrown over 40 TD's in a season, but he is a model of consistancy by tossing over 30 TD's 8 times. Dan Marino and Peyton Manning have done it 4 times.

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Single Season NFL Passing TD Leaders
Rk	Player	Team	TDs	Year
1	Tom Brady	New England Patriots	50	2007
2	Peyton Manning	Indianapolis Colts	49	2004
3	Dan Marino	Miami Dolphins	48	1984
4	Dan Marino	Miami Dolphins	44	1986
5	Kurt Warner	St. Louis Rams	41	1999
T6	Daunte Culpepper	Minnesota Vikings	39	2004
T6	Brett Favre	Green Bay Packers	39	1996
8	Brett Favre	Green Bay Packers	38	1995
T9	Kurt Warner	St. Louis Rams	36	2001
T9	Steve Beuerlein	Carolina Panthers	36	1999
T9	Steve Young	San Francisco 49ers	36	1998
T9	Y.A. Tittle	New York Giants	36	1963
T9	George Blanda	Houston Oilers	36	1961
T14	Steve Young	San Francisco 49ers	35	1994
T14	Brett Favre	Green Bay Packers	35	1997
T14	Tony Romo	Dallas Cowboys	35	2007
T17	Drew Brees	New Orleans Saints	34	2008
T17	Philip Rivers	San Diego Chargers	34	2008
T17	Randall Cunningham	Minnesota Vikings	34	1998
T17	Daryle Lamonica	Oakland Raiders	34	1969
T21	Y.A. Tittle	New York Giants	33	1962
T21	Dan Fouts	San Diego Chargers	33	1981
T21	Warren Moon	Houston Oilers	33	1990
T21	Jim Kelly	Buffalo Bills	33	1991
T21	Brett Favre	Green Bay Packers	33	1994
T21	Warren Moon	Minnesota Vikings	33	1995
T21	Vinny Testaverde	Baltimore Ravens	33	1996
T21	Peyton Manning	Indianapolis Colts	33	2000
T21	Daunte Culpepper	Minnesota Vikings	33	2000
T30	Johnny Unitas	Baltimore Colts	32	1959
T30	Sonny Jurgensen	Philadephia Eagles	32	1961
T30	Lynn Dickey	Green Bay Packers	32	1983
T30	Dave Krieg	Seattle Seahawks	32	1984
T30	Scott Mitchell	Detroit Lions	32	1995
T30	Jeff Garcia	San Francisco 49ers	32	2001
T30	Brett Favre	Green Bay Packers	32	2001
T30	Brett Favre	Green Bay Packers	32	2003
T30	Carson Palmer	Cincinnati Bengals	32	2005

** Updated Jan. 8th, 2009

Sources:
pro-football-reference.com
databasefootball.com
wikipedia.org
espn.com