Buffalo Sabres Schedule
| Date: | Opponent | Game Time: |
| Fri, Oct 10 | Vs. Montreal Canadiens | 7:30 PM |
| Mon, Oct 13 | @ New York Islanders | 2:00 PM |
| Wed, Oct 15 | @ New York Rangers | 7:00 PM |
| Fri, Oct 17 | Vs. Vancouver Canucks | 7:30 PM |
| Sat, Oct 18 | @ Atlanta Thrashers | 7:00 PM |
| Tue, Oct 21 | Vs. Boston Bruins | 7:00 PM |
| Thu, Oct 23 | @ Minnesota Wild | 8:00 PM |
| Sat, Oct 25 | @ Colorado Avalanche | 9:00 PM |
| Sun, Oct 26 | Vs. Ottawa Senators | 7:00 PM |
| Thu, Oct 30 | Vs. Tampa Bay Lightning | 7:00 PM |
| Sat, Nov 01 | Vs. Washington Capitals | 7:00 PM |
| Mon, Nov 03 | @ New Jersey Devils | 7:00 PM |
| Fri, Nov 07 | Vs. Atlanta Thrashers | 7:30 PM |
| Sat, Nov 08 | @ Boston Bruins | 7:00 PM |
| Wed, Nov 12 | Vs. St. Louis Blues | 7:00 PM |
| Fri, Nov 14 | Vs. Columbus Blue Jackets | 7:30 PM |
| Sat, Nov 15 | @ Pittsburgh Penguins | 7:30 PM |
| Wed, Nov 19 | @ Boston Bruins | 7:00 PM |
| Fri, Nov 21 | Vs. Philadelphia Flyers | 7:30 PM |
| Sat, Nov 22 | Vs. New York Islanders | 7:00 PM |
| Wed, Nov 26 | Vs. Boston Bruins | 7:00 PM |
| Fri, Nov 28 | Vs. Pittsburgh Penguins | 7:30 PM |
| Sat, Nov 29 | @ Montreal Canadiens | 7:00 PM |
| Mon, Dec 01 | Vs. Nashville Predators | 7:00 PM |
| Thu, Dec 04 | @ Florida Panthers | 7:30 PM |
| Sat, Dec 06 | @ Tampa Bay Lightning | 7:30 PM |
| Mon, Dec 08 | @ Pittsburgh Penguins | 7:30 PM |
| Wed, Dec 10 | Vs. Tampa Bay Lightning | 7:00 PM |
| Fri, Dec 12 | Vs. Toronto Maple Leafs | 7:30 PM |
| Sat, Dec 13 | @ New Jersey Devils | 7:00 PM |
| Wed, Dec 17 | Vs. New Jersey Devils | 7:00 PM |
| Fri, Dec 19 | Vs. Los Angeles Kings | 7:30 PM |
| Sat, Dec 20 | @ Montreal Canadiens | 7:00 PM |
| Mon, Dec 22 | Vs. Pittsburgh Penguins | 7:00 PM |
| Fri, Dec 26 | @ Washington Capitals | 7:00 PM |
| Sat, Dec 27 | Vs. New York Islanders | 7:00 PM |
| Tue, Dec 30 | Vs. Washington Capitals | 7:00 PM |
| Tue, Jan 01 | @ Toronto Maple Leafs | 7:00 PM |
| Thu, Jan 03 | @ Boston Bruins | 1:00 PM |
| Sun, Jan 06 | Vs. Ottawa Senators | 7:00 PM |
| Wed, Jan 09 | Vs. New York Rangers | 7:30 PM |
| Thu, Jan 10 | @ Detroit Red Wings | 7:00 PM |
| Mon, Jan 14 | @ Chicago Blackhawks | 8:30 PM |
| Tue, Jan 15 | @ Dallas Stars | 8:30 PM |
| Thu, Jan 17 | Vs. Carolina Panthers | 7:00 PM |
| Sat, Jan 19 | @ Florida Panthers | 7:30 PM |
| Mon, Jan 21 | @ Tampa Bay Lightning | 7:30 PM |
| Sun, Jan 27 | @ Edmonton Oilers | 9:00 PM |
| Mon, Jan 28 | @ Calgary Flames | 8:00 PM |
| Thu, Jan 31 | @ Phoenix Coyotes | 9:00 PM |
| Sat, Feb 02 | @ Anaheim Ducks | 10:00 PM |
| Mon, Feb 04 | Vs. Toronto Maple Leafs | 7:30 PM |
| Wed, Feb 06 | Vs. Montreal Canadiens | 7:30 PM |
| Thu, Feb 07 | @ Ottawa Senators | 7:00 PM |
| Mon, Feb 11 | Vs. Ottawa Senators | 7:30 PM |
| Wed, Feb 13 | Vs. San Jose Sharks | 7:30 PM |
| Fri, Feb 15 | Vs. Carolina Panthers | 6:00 PM |
| Sun, Feb 17 | @ Toronto Maple Leafs | 7:30 PM |
| Tue, Feb 19 | @ Philadelphia Flyers | 7:00 PM |
| Thu, Feb 21 | Vs. New York Rangers | 7:00 PM |
| Sun, Feb 24 | Vs. Anaheim Ducks | 7:00 PM |
| Tue, Feb 26 | @ Carolina Panthers | 7:00 PM |
| Thu, Feb 28 | @ New York Islanders | 7:00 PM |
| Tue, Mar 04 | Vs. Montreal Canadiens | 7:30 PM |
| Thu, Mar 06 | Vs. Phoenix Coyotes | 7:30 PM |
| Fri, Mar 07 | @ Ottawa Senators | 7:00 PM |
| Mon, Mar 10 | @ Philadelphia Flyers | 7:00 PM |
| Wed, Mar 12 | Vs. Florida Panthers | 7:00 PM |
| Fri, Mar 14 | Vs. Atlanta Thrashers | 7:00 PM |
| Mon, Mar 17 | @ Ottawa Senators | 7:30 PM |
| Thu, Mar 20 | Vs. Philadelphia Flyers | 7:30 PM |
| Fri, Mar 21 | @ New York Rangers | 7:00 PM |
| Tue, Mar 25 | Vs. Florida Panthers | 7:00 PM |
| Thu, Mar 27 | Vs. Toronto Maple Leafs | 7:30 PM |
| Fri, Mar 28 | @ Montreal Canadiens | 7:00 PM |
| Tue, Apr 01 | @ Atlanta Thrashers | 7:00 PM |
| Thu, Apr 03 | @ Washington Capitals | 7:00 PM |
| Fri, Apr 04 | Vs. New Jersey Devils | 7:00 PM |
| Sun, Apr 06 | Vs. Detroit Red Wings | 7:00 PM |
| Tue, Apr 08 | @ Toronto Maple Leafs | 7:30 PM |
| Wed, Apr 09 | @ Carolina Panthers | 7:00 PM |
| Fri, Apr 11 | Vs. Boston Bruins | 4:00 PM |